5 Times Young Sheldon's Missy Was the Best Sister to Sheldon & 5 Times It Was Penny

Top 5 Times Young Sheldon’s Missy Was the Best Sister to Sheldon and 5 Times It Was The Big Bang Theory’s Penny

Welcome to MsMojo, and today we’re counting down our picks for the times Missy shone as Sheldon’s sister on “Young Sheldon” and the times Penny took on that role in “The Big Bang Theory.”

#5: Missy: Pulling a Splinter Out of Sheldon’s Finger
“Potato Salad, a Broomstick, and Dad's Whiskey”

The twins spend an afternoon home alone after Mary gets a job at the church and can’t find anyone to watch them. It’s all going fine until they spot a shadowy figure outside the window— but don’t worry, Missy’s resourceful. Luckily, that resourcefulness comes in handy when Sheldon panics over a splinter. The siblings end up on a mission to find a pair of tweezers that involves sneaking into their parents’ bedroom, a bottle of whiskey, and a needle. Yet it’s Missy who has the lightbulb or red light-up nose moment that saves the day. Who knows what might’ve been if Missy hadn’t been there to step up in Sheldon’s time of need?

#5: Penny: Giving Sheldon the Talk
“The Opening Night Excitation”

In season six, Penny dares ask Sheldon the question no one else would. When that day finally arrives, he comes to Penny for advice. Now, as we know, Sheldon isn’t keen on physical contact of any kind or discussing emotions, so the fact that he felt comfortable talking to Penny about this all is a huge deal! Like the new “Star Wars” dropping huge! Apparently, Missy already taught him about the birds and the bees when they were kids. However, in anticipation of his big night with Amy, Penny fills in the details we don’t expect a child to know. She essentially acts as Sheldon’s sisterly Yoda, ensuring the “Force Awakens” that night.

#4: Missy: Hugging Sheldon When He Cries
“A High-Pitched Buzz and Training Wheels”

No one throws shade quite like a sibling, right? Indeed, when Sheldon’s bothered by the hum of the refrigerator, she wastes no delivering a savage burn. Now, let’s not forget who convinces Sheldon to dismantle the fridge in the first place. However, when he gets in trouble, she’s initially all too happy to kick back and enjoy the show. Sure, messing with Sheldon is all good fun until it ends in tears. So, the moment she comforts him with a hug is truly heartwarming. We know Sheldon isn’t a hugger, so the fact he reciprocates just melts our hearts. It’s a genuine “aww” moment, reminding us there’s nothing quite like the sibling bond.

#4: Penny: Rescuing Glenn the Battle Ostrich (& Some Other Virtual Stuff)
“The Zarnecki Incursion”

Penny might not exactly understand what “World of Warcraft” means to Sheldon, but she understands that losing a bunch of virtual possessions is a big deal to him. While day-old cheesecake brings him little comfort, his other friends get what’s at stake and join Sheldon on a mission to retrieve the stolen goods. Perhaps they’ve conquered many virtual quests before, but real life is not really their forte. Luckily, they know someone who has enough street smarts for them all. Sure, Penny might not get it, but she gets her friend is upset, and that’s all that matters. We certainly got a kick out of watching her save the day.

#3: Missy: The Walkie-Talkie
“Pish Posh and a Secret Back Room”

Most teens want a space they can make their own and get a bit of privacy. However, Sheldon’s not most teenagers! If there’s one thing he doesn’t like, it’s change. So when Missy suggests taking over Georgie’s old room once he’s moved to the garage, Sheldon’s not exactly on board. In fact, he gets quite distressed. So, they work out a system to keep chatting even after Missy’s moved out. Those walkie-talkies come in handy multiple times, much to Sheldon’s delight and perhaps less to Missy’s. Still, she’s willing to go the extra mile to ease his anxieties, even if it means sacrificing a bit of shut-eye, earning her top marks in the sister department.

#3: Penny: Helping Sheldon Figure Out String Theory
“The Solo Oscillation”

Over the years, Penny and Sheldon form a special bond. She becomes more patient with him, and he starts opening up to her. So when he freaks out over his next career moves, it’s Penny who manages to steer him onto the right path. She lets him vent his frustrations, offers advice, and sits patiently with him as he figures out his next steps. She might not have a clue what he’s talking about, but that doesn’t mean she can’t impart some great advice. Ultimately, with some support and encouragement, Sheldon has a major breakthrough. He’d probably be the last to admit it, but he probably wouldn’t have gotten anywhere without Penny’s help.

#2: Missy: Comforting Sheldon About the Positives of Growing Up
“A Clogged Pore, a Little Spanish and the Future”

As we said, Sheldon isn’t a fan of change. So when he discovers a zit – the first sign of puberty – he’s thrown into a panic about what other changes lie ahead. Cue those trusty walkie-talkies. Although Missy’s not initially thrilled at being woken up by Sheldon’s pre-teen crisis, she can’t turn her back on him in his time of need. They end up having a late-night heart-to-heart where Sheldon shares what scares him about growing up. She responds with some sisterly wisdom, pointing out that there’s also much to look forward to. Thanks to Missy’s pep talk, Sheldon begins to embrace his transition into adulthood.

#2: Penny: Sheldon Opens Up to Her
“The Hot Tub Contamination”

Leonard may be Sheldon’s bestie, and Amy, his girlfriend, but there’s no denying Sheldon may be most comfortable around Penny. Amy sometimes feels a twinge of jealousy over their bond, so perhaps it’s best if she doesn’t know that Sheldon once revealed his deepest, darkest secret to Penny. When Shamy hits a rough patch after moving in together, Penny and Leonard step in to give them some space from each other. While chilling over ice cream, Sheldon opens up to Penny about a childhood trauma that sparked a lifelong habit. He also confesses his fear of repeating his parents’ mistakes. That’s some heavy stuff to lay bare! Luckily, Penny knows just what to say.

Before we unveil our top picks, here are a few honorable mentions.

Missy: Teaching Sheldon About Politics, “A Political Campaign and a Candy Land Cheater”
Her Methods May Be Questionable, but She Knows What Makes a Winner

Penny: Taking Sheldon Shopping, “The Pants Alternative”
She Uses Her Expertise to Help Sheldon in His Time of Need

Missy: Teaching Sheldon to Ride a Bike, “Training Wheels and an Unleashed Chicken”
Well, She Tries to Until His Ornithophobia Gets in the Way

Penny: The Napkin, “The Bath Item Gift Hypothesis”
It Earned Her a Hug from Sheldon!

#1: Missy: Reassuring Sheldon Before Graduation
“Graduation”

As graduation approaches, Sheldon’s excitement about starting college turns into full-blown panic. To make matters worse, his meltdown gets captured by a news crew. Later that night, during one of the twins’ classic late-night chats, Missy reassures Sheldon that he’s not the only one who’s scared of what the future will bring but encourages him to face it head-on anyway. With her words in mind, Sheldon finds the courage to embrace the next chapter. The sweetest moment is when he dedicates his speech to Missy. It’s not often Sheldon shows appreciation, but this is basically his way of saying thank you. Seeing the joy on Missy’s face is enough to melt anyone’s heart.

#1: Penny: Party in the Bathroom
“The Celebration Experimentation”

Sheldon’s childhood birthday parties aren’t exactly fond memories, thanks largely to Missy’s savage streak. Now, with supportive friends and a loving girlfriend, it’s time to make some new and happier memories. However, when the festivities start feeling a bit too much, Sheldon hides out in the bathroom. Penny checks on him and reassures him that she’ll stick by his side no matter where he chooses to spend his party. She also tells him how much he means to her. Eventually, he rejoins the celebrations, and Penny even insists on giving him a birthday hug. The fact that he hugs her back rather than just stands there awkwardly as he once would speaks volumes.

Which brother-sister bond was your favorite? Let us know in the comments.